Synephrine: Side Effects


Synephrine is a substance extracted from the peel of bitter orange (Citrus aurantium), a fruit native to India. Extracted for the first time in 1964, it has always been to raise blood pressure, while today it is mainly taken for slimming properties. Let’s find out the characteristics and side effects of synephrine.


Synephrine: characteristics and properties

The bitter orange from which synephrine is extracted is a small tree with deep green leaves, white flowers similar to those of sweet orange, with orange and wrinkled fruits, rich in essential oils. 

Synephrine is a sympathomimetic amine used for weight loss purposes and as a stimulant and contractor.

Synephrine stimulates thermogenesis (with an increase in calorie consumption), reduces appetite and excites the basal metabolism.


Side Effects of Synephrine

Using synephrine supplements can bring some side effects, such as: 

  • hyperagitation,
  • tachycardia, 
  • arrhythmias, 
  • hypertensive crisis,
  • heart problems in general. 

The intake of synephrine is not recommended during pregnancy and breastfeeding, and in conjunction with other stimulating substances such as caffeine.


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